Renassance of Alchemy is an alchemy-themed worker placement game by Kuro, set in the same world view as his previous title Ars Alchimia.

Each player has three workers, each represented by a die: one 4-sided, one 6-sided and one 8-sided. The smaller the die, the weaker, but quicker. There are roughly two types of places to place, either material-gathering places, which number varies depending on number of players, and the University, which allows players to play upgrade cards from their hand. The four-sided worker allows the player to take the selected action 3 times, the 6-sided twice, and the 8-sided just once. However, the player can strain the worker in order to perform certain extra actions, and this will lower the endurance of the worker – a worker with just 1 endurance cannot be placed. Being pushed out by another player's larger worker will also lower a worker's endurance.

The game is played in 3 "years", each year being divided into the above first phase of gathering of materials and playing cards, and the second phase of completing the tasks of the year. Once a player starts completing tasks, they cannot go back to gather materials, but first to the mill gets more points.

The special upgrade cards that players play when placing a worker on the University customizes the player's various abilities, giving their workers or the laboratory improved or new functions.

Ater 3 years, the collected VP for completing tasks is tallied with bonus points for various things, and most VP wins.

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